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Lang Research Center

Promoting Research in a Community Health Setting

 

 

8th Annual Residents and Fellows Research Day  

 

Nearly 200 physicians, dentists, nurses and other members of the medical staff of New York Hospital Queens gathered on May 14 for presentations of 90 research studies conducted by the hospital’s residents and fellows, and to hear a keynote address given by the American College of Surgeons’ Clifford Y. Ko, M.D., M.S. An annual event sponsored by the hospital’s Theresa and Eugene M. Lang Center for Research and Education, the program develops research skills among doctors-in-training.

Each year, research awards are given to a select number of studies – criteria includes research methodology, potential patient impact, and overall presentation quality. Six studies were honored:

-“Risk Factors for Post-Operative Cognitive Change in Elderly Patients Undergoing Gastrointestinal Surgery” – Jackson Ng, M.D., research fellow, Department of Surgery, with Mitchell Chorost, M.D., director, Surgical Oncology and Associate Director, Cancer Center, et al.

Post-operative cognitive dysfunction (POCD) in the elderly is a growing concern. Cambridge Neuropsychological Test Automated Battery (CANTAB) assessed cognitive changes in an objective and sensitive manner… [This] study revealed that monitoring the pre- and post-operative changes in CANTAB scores provided a more sensitive and objective measurement of post-operative cognitive changes.

-“Rectal Colonization With Carbapenem-Resistant Enterobacteriaceae and Clostridium difficile Among Residents of a Long-Term Care Facility” – George Labaze, M.D., fellow, Division of Geriatrics and Palliative Care, with Sorana Segal-Maurer, M.D., director, The Dr. James J. Rahal Jr. Division of Infectious Diseases, et al.

The Centers for Disease Control and Prevention (CDC) has labeled carbapenem-resistant Enterobacteriaceae (CRE) and C. difficile (CDIFF) urgent threats requiring mandatory reporting. Residents of long-term care facilities (LTCF) are at increased risk for colonization of these pathogens… [Results showed] high prevalence of CRE and/or CDIFF rectal colonization among asymptomatic LTCF residents.

-“Breast Conservation Therapy in Early-Stage Female Breast Cancer Patients Age <40 is not Inferior to Mastectomy: A Surveillance, Epidemiology and End Results Data Analysis” – Jason C. Ye, M.D., resident, Department of Radiation Oncology, with Akkamma Ravi, M.D., clinical director and attending physician, Department of Radiation Oncology, NYHQ, and associate professor of radiation oncology, Weill Cornell Medical College, et al.

Breast conserving therapy (BCT) consisting of partial breast surgery and radiation therapy allows for sparing of the normal breast tissue and results in better cosmesis and fewer side effects, such as lymphedema, in patients with early-stage breast cancer. However, young patients tend to receive mastectomy as surgical treatment. [The researchers aimed] to examine the difference between outcomes in young women (age <40) treated with BCT versus mastectomy… [Findings showed that] patients aged 40 and younger with stage I and II invasive breast cancer treated with BCT had non-inferior cause-specific survival than mastectomy, regardless of estrogen receptor status. [This] data suggest that young age and/or estrogen receptor status is not a contraindication to BCT in early-stage breast cancer patients.

-“Ketamine Abuse Syndrome: An Emerging Pattern of Hepatobiliary and Urinary Pathology” – Jessica W. Wang, M.D., resident, Department of Pediatrics, Violetta Kivovich, M.D., resident, Department of Pediatrics, and Laurie Gordon, M.D., director, Inpatient Unit, Department of Pediatrics.

Ketamine is a dissociative anesthetic. It has become popular as a drug of abuse, most notably in East Asia. Recent case reports have emerged, linking ketamine abuse with urinary and hepatic abnormalities. Between 2011 and 2013, the Pediatric Department at NYHQ noted a pattern of hepatic and urinary symptoms among teenagers and young adult patients of East Asian descent. Each of these patients ultimately endorsed ketamine abuse. [The researchers] present a case series of six patients, illustrating the presentation of this newly recognized ketamine abuse pattern (KAP).

-“Dissemination of Invasive Aspergillosis: Diagnostic and Management Dilemmas” – Mark Vinelli, D.O., resident, Department of Medicine, and Roxana Lazarescu, M.D., associate program director, Internal Medicine Residency Program.

Aspergillosis species are ubiquitous fungus in the external environment and inhalation of infectious conidia is a common event. However, tissue invasion is uncommon and occurs most frequently in the setting of immunosuppression. Disseminated aspergillosis is an uncommon but frequently fatal disease in critically ill patients. [The researchers present] a case where diagnosis was unfortunately made during autopsy.

-“Ethical Prospective of Drug Therapy Clinical Trials and Their Effect on Patient Health” – Sharmila Tilak, M.D., resident, Department of Medicine, Mark Vinelli, D.O., resident, Department of Medicine, and Roxana Lazarescu, M.D., associate program director, Internal Medicine Residency Program.

With the advances in bioengineering, many researchers are employing immune-modulation therapy as a therapeutic strategy against various diseases. During the testing phase of a drug trial, patients are susceptible to unknown risks and side effects. [The researchers present a case report that aimed to] raise awareness of patients presenting with complications secondary to drug therapy undergoing clinical investigation.

 

  Keynote Address, “Achieving Optimal Care in Surgery: Observations from the American College of Surgeons”

In his keynote address, Dr. Clifford Ko, Director, Division of Research and Optimal Patient Care and Director, National Surgical Quality Improvement Program (NSQIP), American College of Surgeons, spoke about best practices to reduce surgical site infection rates and improve overall surgical outcomes. 

News Briefs

This year's keynote speaker at Residents and Fellows Research Day on May 14 is Clifford Y. Ko, M.D., M.S.H.S., F.A.C.S., F.A.S.C.R.S.  He will speak on "Achieving Optimal Care in Surgery: Observations from the American College of Surgeons."

GRADE Study.  (Glycemia Reduction Approaches in Diabetes) Do you have type 2 diabetes?  Help to find the best long-term treatment for people with diabetes.  Most people with diabetes need metformin and another drug to keep blood sugar close to normal.  We are comparing four potential second line treatments in the GRADE study to determine which one, when added to metformin, is best for controlling diabetes.  All four treatments are recommended by the American Diabetes Association and FDA approved.  Visit https://grade.bsc.gwu.edu and call 718-670-2914, or 718-670-1827.

Full details on how to participate in Research Day 2014 are available today at Research Day 2014 Basic Information. 

May 14 is the date for the 8th annual Residents and Fellows Research Day.  This is a special opportunity for residents and fellows to showcase their reserach, with the assistance of the Lang Research Center Staff.

Holly Andersen Scholar Named. Michaela Greenbaum, a pre-med student, is the Lang Research Center's second Dr. Holly Andersen Scholar.  Ms. Grenbaum serves as the assistant study coordinator for the Type 2 Diabetes GRADE Study, a NIH sponsored study of diabetes treatment, led by Daniel Lorber, M.D. and Phyllis August, M.D., M.P.H.

The Theresa and Eugene M. Lang Center for Research and Education has joined the Maternal-Fetal Medicine Units Network with Columbia University Medical Center, one of 14 clinical centers in the network.

The network conducts clinical studies to improve maternal, fetal and neonatal health with an emphasis on randomized-controlled trials.  The goal is to reduce maternal, fetal and infant morbidity related to preterm birth, fetal growth abnormalities and maternal complications as well as to provide insight on evidence-based, cost-effective obstetric practice

Our researchers are making news.  Look here for their latest professional accomplishments and activities.

The National Institutes of Health has created a new Web site to help people learn more about clinical trials, why they matter, and how to participate.  Read their announcement here.

 
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