An autoimmune disorder is any reaction or attack of a person's immune system against its own organs and tissues. In the liver, the immune system can destroy liver cells and damage bile ducts. Chronic active hepatitis can be caused by an autoimmune disorder.
In autoimmune hepatitis, the body's own immune system destroys the cells of the liver. It may be classified as type 1 or type 2. Type 1 (classic) is the most common form. It may occur at any age, but usually affects young women more than men. Also, other autoimmune disorders can be associated with type 1 such as thyroiditis, Grave's disease, and ulcerative colitis. Type 2 autoimmune hepatitis generally affects girls between the ages of two and 14, but occurs in adults, too.
Two main metabolic disorders affect the liver:
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Online Resources of Liver, Biliary, & Pancreatic Disorders