CVID is an immunodeficiency disorder characterized by a low level of antibodies, making it difficult for the child's body to fight diseases. The child then becomes sick with recurrent infections. The disease may become evident during infancy, during childhood or puberty, or even later into adulthood. The symptoms of the disease are very different for each child affected, which is why it is called a variable group of disorders.
The cause of CVID is unknown. The disorder is characterized by a decrease in the number of immunoglobulins (antibodies) in the affected person. Immunoglobulins are produced by the body and are necessary in fighting infections. In some cases, more than one individual in a family may be affected.
The following are the most common symptoms of CVID. However, each child may experience symptoms differently. Symptoms may include:
A diagnosis of CVID is usually made based on a complete medical history and physical examination. In addition, multiple blood tests may be ordered to help confirm the diagnosis, and testing for low serum IgG concentrations is primary to diagnose this condition.
Specific treatment for CVID will be determined by your child's doctor based on:
Treatment may include:
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