Drug rashes are the body's reaction to a certain medication. The type of rash that occurs depends on the type of drug that is causing it. Rashes can range from mild to severe.
Rashes caused by drugs can be categorized in the following groups:
Drug rashes may be severe and require hospitalization. Contact your child's doctor immediately.
Type of rash | Symptoms | Possible causes |
---|---|---|
Acne | PImples and red areas that appear most often on the face, shoulders, and chest | Anabolic steroids, corticosteroids, bromides, iodides, hydantoins, lithium, isoniazid, phenytoin, phenobarbital, vitamins B2, B6, and B12 |
Exfoliative dermatitis | Red, scaly skin that may thicken and involve the entire body | Antibiotics that contain sulfa, penicillins, and hydantoins |
Fixed drug eruption | A dark red or purple rash that recurs at the same site on the skin | Antibiotics that contain sulfa, tetracycline, and phenolphthalein (found in certain laxatives) |
Hives | Raised red bumps | Aspirin, penicillins, antibotics that contain sulfa, and many other drugs |
Morbilliform or maculopapular rash | A flat, red rash which may include pimples similar to the measles | Antibiotics that contain sulfa, ampicillin, analgesics, and barbiturates are the more common causative drugs; however, any drug can cause this rash |
Purpuric eruptions | Purple areas on the skin, often on the legs | Some anticoagulants and diuretics |
Stevens-Johnson syndrome | Blisters or a hive-like rash on the lining of the mouth, vagina, or penis | Antibiotics that contain sulfa, NSAIDs, barbiturates, penicillins, and other antibiotics |
Diagnosing a rash caused by a reaction to medication is complicated. Even a small amount of a drug can cause a major reaction in the skin. In addition, the reaction can occur even after the patient has taken a medication for a long period of time.
Your child's doctor will usually advise you to have your child stop taking any medication that is not necessary to sustain life, to see if the reaction stops. Other medications may be substituted, if possible.
Specific treatment for drug rashes will be determined by your child's doctor based on:
The condition usually clears up if the patient stops taking the medication that is causing the reaction. Other treatment may include:
Allergic reactions can be serious and even fatal. If your child has acute symptoms in addition to the rash, such as wheezing, difficulty breathing, tightness in the throat or chest, fainting, nausea, vomiting, or other serious symptoms, you should call your child's doctor immediately or call 911.
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