(Retrograde Ureteropyelogram, Retrograde Pyelography, Retrograde Ureteropyelography)
A retrograde pyelogram is a type of X-ray that allows visualization of the bladder, ureters, and renal pelvis. Generally, this test is performed during a procedure called cystoscopy—evaluation of the bladder with an endoscope (a long, flexible lighted tube). During a cystoscopy, contrast dye, which helps enhance the X-ray images, can be introduced into the ureters via a catheter.
As the techniques and technology of ultrasound (high-frequency sound waves) and contrast dye have improved, other procedures such as CT (computed tomography) scan and renal ultrasound have become more commonly used than retrograde pyelography.
X-rays use invisible electromagnetic energy beams to produce images of internal tissues, bones, and organs on film. X-rays are made by using external radiation to produce images of the body, its organs, and other internal structures for diagnostic purposes. X-rays pass through body structures onto specially-treated plates (similar to camera film) and a "negative" type picture is made (the more solid a structure is, the whiter it appears on the film).
Other related procedures that may be used to diagnose problems of the upper urinary tract include kidney, ureters, and bladder (KUB) X-ray, CT (computed tomography) scan of the kidneys, renal ultrasound, renal angiogram, intravenous pyelogram, antegrade pyelogram, and renal venogram. Please see these procedures for additional information.
The body takes nutrients from food and converts them to energy. After the body has taken the food that it needs, waste products are left behind in the bowel and in the blood.
The urinary system keeps chemicals, such as potassium and sodium, and water in balance, and removes a type of waste, called urea, from the blood. Urea is produced when foods containing protein, such as meat, poultry, and certain vegetables, are broken down in the body. Urea is carried in the bloodstream to the kidneys.
Other important functions of the kidneys include blood pressure regulation, and the production of erythropoietin, which controls red blood cell production in the bone marrow.
Two kidneys. A pair of purplish-brown organs located below the ribs toward the middle of the back. Their function is to:
The kidneys remove urea from the blood through tiny filtering units called nephrons. Each nephron consists of a ball formed of small blood capillaries, called a glomerulus, and a small tube called a renal tubule. Urea, together with water and other waste substances, forms the urine as it passes through the nephrons and down the renal tubules of the kidney.
Two ureters. These narrow tubes carry urine from the kidneys to the bladder. Muscles in the ureter walls continually tighten and relax, forcing urine downward, away from the kidneys. If urine backs up, or is allowed to stand still, a kidney infection can develop. About every 10 to 15 seconds, small amounts of urine are emptied into the bladder from the ureters.
Bladder. The bladder is a triangle-shaped, hollow organ located in the lower abdomen. It's held in place by ligaments that are attached to other organs and the pelvic bones. The bladder's walls relax and expand to store urine, and contract and flatten to empty urine through the urethra. The typical healthy adult bladder can store up to two cups of urine for two to five hours.
Two sphincter muscles. These circular muscles help keep urine from leaking by closing tightly like a rubber band around the opening of the bladder.
Nerves in the bladder. These nerves alert a person when it's time to urinate, or empty the bladder.
Urethra. This tube allows urine to pass outside the body.
A retrograde pyelogram may be used in people suspected to have an obstruction, such as a tumor, stone, blood clot, or stricture (narrowing) in the kidneys or ureters. It evaluates the lower portion of the ureter to which urine flow is obstructed. A retrograde pyelogram is also used to evaluate placement of a catheter or a ureteral stent—a hollow tube that allows passage of urine around an obstruction.
An advantage of the retrograde pyelogram is that it can be performed even if the patient is allergic to contrast dye because a minimal amount of the contrast dye is absorbed by the body (unlike another more common test called an intravenous pyelogram). The procedure may also be performed on people with impaired kidney function.
There may be other reasons for your physician to recommend a retrograde pyelogram.
You may want to ask your physician about the amount of radiation used during the procedure and the risks related to your particular situation. It's a good idea to keep a record of your past history of radiation exposure, such as previous scans and other types of X-rays, so that you can inform your physician. Risks associated with radiation exposure may be related to the cumulative number of X-ray examinations and/or treatments over a long period of time.
If you're pregnant or suspect that you may be pregnant, you should notify your physician. Radiation exposure during pregnancy may lead to birth defects.
If contrast dye is used, there's a risk for allergic reaction to the dye. Patients who are allergic to or sensitive to medications, contrast dye, or iodine should notify their physician.
Patients with kidney failure or other kidney problems should notify their physician. In some cases, the contrast dye can cause kidney failure, especially if the person is taking Glucophage (a diabetic medication).
Possible complications of retrograde pyelogram include, but are not limited to, sepsis, urinary tract infection, bladder perforation, hemorrhage, nausea, and vomiting.
A retrograde pyelogram may be contraindicated for patients experiencing severe dehydration.
There may be other risks depending on your specific medical condition. Be sure to discuss any concerns with your physician prior to the procedure.
Certain factors or conditions may interfere with a retrograde pyelogram. These factors include, but are not limited to:
A retrograde pyelogram may be performed on an outpatient basis or as part of your stay in a hospital. Procedures may vary depending on your condition and your physician's practices.
Generally, the retrograde pyelogram follows this process:
Your recovery process will vary depending on the type of procedure performed and your physician’s practices. After the procedure, you'll be taken to the recovery room for observation. Once your blood pressure, pulse, and breathing are stable and you're alert, you'll be taken to your hospital room or discharged to your home.
Your urine output will be monitored closely for volume and signs of blood. It may be red from even a small amount of blood. This is considered normal and doesn't necessarily indicate a problem. You may be instructed to continue monitoring your urine output for a day or so once you are at home.
You may experience pain when you urinate. Take a pain reliever for soreness as recommended by your physician. Aspirin or certain other pain medications may increase the chance of bleeding. Be sure to take only recommended medications.
Notify your physician to report any of the following:
Your physician may give you additional or alternate instructions after the procedure, depending on your particular situation.
The content provided here is for informational purposes only, and wasn't designed to diagnose or treat a health problem or disease, or to replace the professional medical advice you receive from your physician. Please consult your physician with any questions or concerns you may have regarding your condition.
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